| Customization: | Available |
|---|---|
| CAS No.: | 57029-18-2 |
| Formula: | C22h30cl2n10 |
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Polyhexamethylene Guanidine Hydrochloride PHMG 50% Solution has been widely used as a new generation of guanidine disinfectants, its derivatives. In recent years, there are many research reports at home and abroad. Its high polymer structure reduces its toxicity. But the bactericidal effect is more excellent, which has been widely used in medical and health institutions, family life, food industry, animal husbandry and other fields. Through more and more scholars' research on the properties and efficacy of guanidine disinfectant, its application has been developed continuously.
Methylguanidine in Polyhexamethylene Guanidine Hydrochloride PHMG 50% Solution has high activity, which makes the polymer positive electric and easy to be adsorbed by bacteria and virus, thus inhibiting the division function of bacteria and virus and making it lose the ability of reproduction. Moreover, the formation of Polyhexamethylene Guanidine Hydrochloride PHMG 50% Solution blocks the respiration channel of microorganism and makes microorganism suffocate and die.
The damage mechanism of polyhexamethylene guanidine hydrochloride to Escherichia coli cell membrane was studied by β-galactosidase activity analysis, fluorescein isothiocyanate confocal laser scanning microscope, automatic scanning electron microscope and transmission electron microscope. The results showed that low dose polyhexamethylene guanidine had slight damage to bacterial outer membrane and increased the permeability of cell membrane, but no fine particles were found the cells had obvious morphological damage. High dose of p Polyhexamethylene Guanidine Hydrochloride PHMG Solution can collapse the membrane structure, lead to the formation of transmembrane stomata, seriously damage the structure of the cell, break the cell membrane, and release the substances inside the cell.
Applications:
1. Medical disinfection
Polyhexamethylene Guanidine Hydrochloride PHMG 50% Solution has good bactericidal effect on bacteria, fungi and some viruses. However, due to the influence of many factors, polyhexamethylene guanidine compounds as medical disinfectants are mainly compounded with alcohols and other synergistic components. The compound guanidine disinfectant not only improves the germicidal efficacy, but also reduces the adverse reactions, which is more convenient for popularization and application. Some scholars have studied the possibility of the compound of Polyhexamethylene Guanidine Hydrochloride PHMG 50% Solution and didecyldimethyl ammonium chloride, benzalkonium bromide, ethanol, chlorhexidine acetate. The results show that the compound polyhexamethylene biguanide disinfectant has better germicidal efficacy.
2. Disinfection of fruits, vegetables and tableware
Using Polyhexamethylene Guanidine Hydrochloride PHMG 50% Solution to disinfect tableware can make the total number of bacteria and coliform group on the tableware surface meet the requirements of relevant national health standards. After 30 minutes, the value of E.coli pair on the surface of cucumber was decreased by 3.35, and the killing effect of natural bacteria on the surface of fruits and vegetables was also very good. Compared with chlorine containing disinfectant or peroxide disinfectant, Polyhexamethylene Guanidine Hydrochloride PHMG 50% Solution is much less toxic, corrosive and irritant, which is more beneficial to environmental protection.
3. Disinfection of aquaculture
The results showed that this product had a very good killing effect on Vibrio parahaemolyticus, Vibrio alginolyticus, Vibrio floating, Vibrio harveyi, Vibrio anguillarum and Vibrio Bombyx, and no toxicity on the development and survival of abalone, prawn, turbot and sea cucumber It can be used for disinfection of marine culture environment. Adding the product in the process of water circulation treatment can enhance the activity of water, reduce the ammonia and phosphate in water, control the growth of algae, and naturally balance the ecosystem of sea cucumber pond and fish and shrimp pond.
In addition, Polyhexamethylene Guanidine Hydrochloride PHMG 50% Solution is also widely used in the production of beverages, beer and food in foreign countries to disinfect pipes, containers and plant floors, and to remove algae from lakes, ponds, cooling towers and fountains. It can also be used in oil exploitation and mildew prevention of interior and surface of various building materials.
| Property | Technical Analysis and Physical | ||
| Product model | PHMG-98% | PHMG-50% | PHMG-25% |
| Appearance | White powder | Clear colorless to light yellow liquid | Clear colorless to light yellow liquid |
| Assay, % ≥ | 98 | 50 | 25 |
| pH, (10% Solution) | 9.0 - 11.0 | 4.0 - 10.0 | 4.0 - 10.0 |
| Density (20ºC) | 1.039 - 1.046 | 1.080 - 1.120 | 1.039 - 1.046 |
| Boiling Point(ºC) | 102 | |
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PACKING
25kgs/drum 200kgs/drum
STORAGE
Store at room temperature and protect from moisturing to keep the shelf life of material longer and indefinite.
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